Intravenous infusion is one of the commonly used treatment methods. The compatibility of drugs and infusion devices (infusion sets) is an important factor influencing the safety of intravenous infusion of drugs. In order to standardize the use of infusion sets and ensure that patients' medication is safe and effective, it is necessary to be very cautious in the selection of infusion sets. The followings are the selection requirements of clinical drug infusion for
infusion sets.
1. Matters needing attention when choosing the material of the infusion set (PVC and non-PVC)
Traditional infusion sets are mostly made of PVC, which is a thermoplastic resin polymerized by vinyl chloride under the action of an initiator. Ordinary PVC resin powder has no application value, and plasticizers, stabilizers, lubricants, etc. must be added before use.
The PVC infusion set used clinically has the advantages of cheap price, small size, lightweight, convenient clinical application, etc., and is widely used. However, there are also many serious problems in practical applications, which are mainly reflected in the following aspects.
(1) PVC adsorbs (or reacts with drugs) to certain drugs;
(2) In order to increase the flexibility and resilience of the PVC infusion set during the production process, 35%-40% of the plasticizer needs to be added, and the plasticizer DEHP has a toxic effect on multiple systems of the human body. Drugs containing polyoxyethylene castor oil, cyclodextrin derivatives, propylene glycol, ethanol, or benzyl alcohol as solubilizers can accelerate the dissolution of DEHP and induce toxic reactions.
From the perspective of the safety and effectiveness of drug infusion, BQ+ can provide users and patients with a safe choice of PVC-free infusion sets, which can ensure the safety of intravenous drugs.
2. Relevant requirements for the use of a light-proof infusion set
Many drugs in the clinic, such as sodium nitroprusside, nitroglycerin, fleroxacin, etc., can accelerate the oxidation of the drug during the infusion process, and cause the photochemical degradation of the drug, which not only reduces the potency of the drug, but also causes discoloration and precipitation, seriously affect the quality of the drug, and even increase the toxicity of the drug.
Some drugs with poor stability are often made into powder injections and kept in a tightly sealed way, protected from light. After dissolution, due to their low stability and the effect of light, the drugs can undergo oxidation, decomposition, and discoloration.
Therefore, photosensitive drugs need to be protected from light during the production, transportation, and storage process, and some drugs are required to be protected from light even during installation.
The traditional way to avoid light during the clinical infusion of drugs is to use old dark cloth or plastic bags to avoid light. The operation is cumbersome and complicated. Liquid volume and other conditions are time-consuming and labor-intensive.
BQ+ provides an effective light-proof vein set, which is specially used for anti-cancer treatment, which not only meets the needs of clinical anti-cancer drug infusion but also improves the efficiency of anti-cancer drug infusion.
3. Relevant requirements for the filter aperture of the infusion set
Because of the characteristics of the drug and the limitations of the infusion production process, microparticles are an inevitable "component" of the infusion, but the number and size of the microparticles contained in different varieties are different. Studies have found that the particles in the liquid medicine may cause acute reactions or potential dangers after entering the human body through the vein, and the harm is serious and long-lasting.
How to avoid or reduce the damage of particles to the human body is a topic that medical staff must consider. Using a precision infusion set with a filtering device at the terminal is an effective way to reduce the entry of large particles into the human body.
Some drugs are administered by intravenous infusion, which has strict requirements on the filter aperture of the infusion set. The filter membrane of the existing ordinary disposable infusion set in China can only filter particles with a diameter greater than 15 microns, and cannot filter particles with a diameter less than or equal to 15 microns.
With the development of new drugs, new requirements have been put forward for the infusion set, and the clinical needs of the infusion set that can filter particles with a diameter of 5 microns and smaller.
BQ+ has many years of experience in manufacturing infusion sets with precision filters, which meets the ISO 80369-7 standard in the medical industry.
Intravenous treatment is inseparable from the use of infusion sets. In addition to the many requirements in the above selection, we also need to pay attention to many things in the actual use process. If you want to know more about the infusion set after reading the above, you can get a comprehensive solution by contacting us.
As one of the world's leading manufacturers of
medical products, BQ+ has more than 450 types of medical parts for you to choose from and also provides R&D customized services for customers with special requirements. We do our utmost to pay attention to the health of patients, have established a strict quality inspection system, and are committed to providing customers with safe and high-quality products. Our complete management team can provide customers with thoughtful one-stop service. If you want to buy our high-quality infusion set, please contact us immediately!