This article mainly introduces the adverse effects of traditional PVC infusion set in use, specifically in the following aspects:
1. Most plasticizers used in traditional PVC infusion sets are DEHP, and the amount added is about 35%-40%. DEHP will migrate out during the infusion process and enter the human body with the liquid medicine. Animal experiments show that DEHP has reproductive toxicity and developmental toxicity, which can cause malformations of the male reproductive system. DEHP can also directly act on the fetus, and it can also affect fetal development by interfering with the placental barrier. DEHP is also carcinogenic and can cause liver cancer and testicular cancer.
Common drugs that promote the precipitation of DEHP are: paclitaxel, amiodarone hydrochloride, fat emulsion, docetaxel, ciprofloxacin, cefoperazone sodium, fluconazole, metronidazole, chloramphenicol, cimetidine, cyclosporine Hydrocortisone, Hydrocortisone, Hydroprednisone, Prednisone Acetate Injection, etc.